Analysis of drugs and metabolites by gas chromatography-mass spectrometry
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Analysis of drugs and metabolites by gas chromatography-mass spectrometry by Benjamin J. Gudzinowicz

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Published by M. Dekker in New York .
Written in English


Book details:

Edition Notes

Statementby Benjamin J. Gudzinowicz,Michael J. Gudzinowicz ; with the assistance of Horace F. Martin, James L. Driscoll.
ContributionsGudzinowicz, Michael J.
ID Numbers
Open LibraryOL20143010M
ISBN 100824766512

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The second edition of Gas Chromatography and Mass Spectrometry: A Practical Guide follows the highly successful first edition by F.G. Kitson, B.S. Larsen, and C.N. McEwen (), which was designed as an indispensable resource for GC/MS practitioners regardless of whether they are a novice or well experienced. The Fundamentals section has been. Analysis of drugs and metabolites by gas chromatography--mass spectrometry. New York: M. Dekker, © (OCoLC) Online version: Gudzinowicz, Benjamin J. Analysis of drugs and metabolites by gas chromatography--mass spectrometry. New York: M. Dekker, © (OCoLC) Document Type: Book: All Authors / Contributors. Gas chromatography–mass spectrometry (GC-MS) is an analytical method that combines the features of gas-chromatography and mass spectrometry to identify different substances within a test sample. Applications of GC-MS include drug detection, fire investigation, environmental analysis, explosives investigation, and identification of unknown samples, including that of . Mass spectrometry (MS) is a powerful analytical tool with many applications in pharmaceutical and biomedical field. The increase in sensitivity and resolution of the instrument has opened new dimensions in analysis of pharmaceuticals and complex metabolites of biological systems. Compared with other techniques, mass spectroscopy is only the technique for molecular Author: Uttam Singh Baghel, Atamjit Singh, Deeksha Singh, ManishSinha.

Abstract. Gas chromatography-mass spectrometry (GC-MS) has been used for the identification of drugs since when Hammar and coworkers () employed this technique for the analysis of chlorpromazine and some of its metabolites isolated from human by: 2. Role of computers in gas chromatography-mass spectrometry: detection, identification, and quantification in drug metabolism research.- A real time gas chromatograph-mass spectrometer minicomputer system for selected ion analysis.- Drug Abuse.- Can gas chromatography - mass spectrometry influence trends in drugs abuse? Analysis of a biological matrix cont aining cocaine and its metabolites, through gas chromatography with detection by mass spectrometry. Figure 4 represents the identification of the co caine peak. Analysis of Mammalian Cell Proliferation and Macromolecule Synthesis Using Deuterated Water and Gas Chromatography-Mass Spectrometry by Victoria C. Foletta 1, Michelle Palmieri 2,3, Joachim Kloehn 4, Shaun Mason 1, Stephen F. Previs 5, Malcolm J. McConville 4, Oliver M. Sieber 2,3,6,7, Clinton R. Bruce 1 and Greg M. Kowalski 1,*Cited by: 6.

Gas Chromatography–Mass Spectrometry-Based Metabolomic Analysis of Wagyu and Holstein Beef by Tomoya Yamada *, Mituru Kamiya and Mikito Higuchi Division of Livestock Feeding and Management, National Agriculture and Food Research Author: Tomoya Yamada, Mituru Kamiya, Mikito Higuchi. Mass spectrometry is uniquely suited for the analysis of drugs and metabolites for several reasons: only a minimal amount of sample preparation is needed, closely related compounds can be analyzed in a single step, structures can often be deduced directly from the mass spectra without the need for pure reference spectra, and constituents can be.   Introduction. Drug abuse is a major cause of social problems worldwide. The prevalence of drugs of abuse, including marijuana, cocaine, heroin, hallucinogens and prescription-type drugs used nonmedically in the USA from to , was –% (∼20 million people) among individuals who were at least 12 years old ().Among these abused Cited by: Currently, only a few thousand metabolites (>14,) can be measured, when an estimation of , up to one million metabolites are expected to Author: Joachim Kopka.